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Deep tissue imaging

Deep tissue imaging is a fundamental research method in the field of biological imaging. In the field of biological imaging, deep tissue imaging has always been an essential study tool in peering deep within biological structures and monitoring biological interactions. Deep tissue imaging is made possible with the cooperation of many fields including spectroscopy, advanced imaging, microscopy, optics, and mechanics.
Typical examples of deep tissue imaging techniques:
- 2-photon microscopy
- adaptive optics microscopy
- light sheet microscopy

Publications

A Short Review of Deep Tissue Imaging Techniques and Applications

Song J, Dean Z - Journal of Physics: Conference Series - 2022

10.1088/1742-6596/2287/1/012028

Deep tissue fluorescence imaging andin vivobiological applications

Crosignani V, Dvornikov A, Aguilar J, Stringari C, Edwards R, Mantulin W, Gratton E - Journal of Biomedical Optics - 2012

10.1117/1.JBO.17.11.116023

IMAGED OBJECTS
cells, organs

Deep tissue imaging in Helmholtz Imaging CONNECT:

Modality
Light sheet fluorescence microscopy (LSFM)

Light sheet fluorescence microscopy (LSFM) is a fluorescence microscopy technique with an intermediate-to-high optical resolution, but good optical sectioning capabilities and high speed. In contrast to epifluorescence microscopy only a thin slice (usually a few …

Light Sheet Microscopy is a special fluorescence microscopic technique in which only a thin layer in the sample is illuminated, typically a few micrometers. Compared to conventional fluorescence microscopy, this results in better resolution and …

In Helmholtz Imaging CONNECT
➤Applications: 4 ➤Facilities: 0 ➤Centers: 3 ➤Instruments: 0 ➤Labs: 0 ➤Experts: 2 ➤Solutions: 0
Modality
Optical Microscopy

The optical microscope, also referred to as a light microscope, is a type of microscope that commonly uses visible light and a system of lenses to generate magnified images of small objects. Optical microscopes are …

In Helmholtz Imaging CONNECT
➤Applications: 1 ➤Facilities: 4 ➤Centers: 6 ➤Instruments: 5 ➤Labs: 2 ➤Experts: 6 ➤Solutions: 3
Modality
Short wave infrared imaging (SWIR)

Shortwave infrared (SWIR) imaging refers to the use of cameras or sensors that are sensitive to light in the SWIR region of the electromagnetic spectrum, typically between 900 and 2500 nanometers in wavelength. SWIR imaging …

In Helmholtz Imaging CONNECT
➤Applications: 1 ➤Facilities: 0 ➤Centers: 3 ➤Instruments: 2 ➤Labs: 2 ➤Experts: 3 ➤Solutions: 0
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Center
Deutsches Elektronen-Synchrotron (DESY)

DESY is one of the world’s leading accelerator centres. Researchers use the large-scale facilities at DESY to explore the microcosm in all its variety – from the interactions of tiny elementary particles and the behaviour …

In Helmholtz Imaging CONNECT
➤Applications: 153 ➤Facilities: 4 ➤Instruments: 21 ➤Labs: 85 ➤Modalities: 236 ➤Experts: 33 ➤Solutions: 4
Center
Deutsches Krebsforschungszentrum (DKFZ)

More than 450,000 people are diagnosed with cancer each year in Germany. Cancer is a disease that poses enormous challenges to research, because every cancer is different and its course can vary immensely even from …

In Helmholtz Imaging CONNECT
➤Applications: 40 ➤Facilities: 0 ➤Instruments: 6 ➤Labs: 17 ➤Modalities: 31 ➤Experts: 29 ➤Solutions: 9
Center
Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (HMGU)

Helmholtz Zentrum München is the German Research Center for Environmental Health. It investigates important common diseases which develop from the interaction of lifestyle, environmental factors and personal genetic background, focusing particularly on diabetes mellitus, allergies …

In Helmholtz Imaging CONNECT
➤Applications: 24 ➤Facilities: 1 ➤Instruments: 1 ➤Labs: 6 ➤Modalities: 25 ➤Experts: 13 ➤Solutions: 3
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Lab
SWIR imaging

We research the next generation of biomedical imaging techniques.

With noninvasive approaches, we aim to advance both biological research and clinical practice by developing new targeted contrast agents and novel imaging modalities.

In Helmholtz Imaging CONNECT
➤Applications: 1 ➤Facilities: 0 ➤Centers: 2 ➤Instruments: 1 ➤Modalities: 4 ➤Experts: 1 ➤Solutions: 0
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